England became interested in America in the late 16th century, with the first attempted colonization in the early 17th century.The Mayflower sailed to America in September 1620.The Mayflower set sail from Plymouth, England.The people wanted to leave England for America to escape religious persecution and seek economic opportunities.The Mayflower reached America in November 1620.There were 102 passengers on board the Mayflower, including Pilgrims and other settlers.The passengers called the new country "New England."