To solve this expression, we first need to calculate the result.

(AD10^16 + 12^3) 2^4
= (10^16 + 12^3) 2^4 (converting AD10 to decimal)
= (10000000000000000 + 1728) 16 (calculating the powers)
= 10000000000001728 16 (adding the numbers)
= 160000000000274048 (multiplying by 16)

Now, we have the result in decimal: 160000000000274048

Converting this result to different number systems:

Binary: 111001011000101110100000001010110001110000000
Octal: 71605610005276300
Decimal: 160000000000274048
Hexadecimal: 248B507503C1B0

So the result in binary is 111001011000101110100000001010110001110000000, in octal is 71605610005276300, in decimal is 160000000000274048, and in hexadecimal is 248B507503C1B0.