5/16 - (3/16 + 1/3)

First, let's simplify the expression inside the parentheses:

3/16 + 1/3 = (3/16 3/3) + (1/3 16/16)
= 9/48 + 16/48
= 25/48

Now, subtract this value from 5/16:

5/16 - 25/48

To subtract two fractions, we need a common denominator. The least common multiple of 16 and 48 is 48.

Rewrite 5/16 as an equivalent fraction with denominator 48:

5/16 = (5/16 * 3/3) = 15/48

Now, subtract:

15/48 - 25/48 = (15 - 25)/48 = -10/48 = -5/24

Therefore, 5/16 - (3/16 + 1/3) = -5/24.