45% + 15% ÷ 3% × 23% - 43% - 35%
= 45 + 0.15 ÷ 0.03 × 0.23 - 43 - 35
= 45 + 5 × 0.23 - 43 - 35
= 45 + 1.15 - 43 - 35
= 46.15 - 78
= -31.85

Therefore, the result of the expression is -31.85.