4 + 5 8000008654 / 6843 - 7593 - 78604 100000

= 4 + 58238646270 / 6843 - 7593 - 7860400000
= 4 + 8510615562 - 7593 - 7860400000
= 8510615562 - 7589 - 7860400000
= 8510615562 - 7860407589
= 6505653973

So, the answer is 6,505,653,973.